Misis, near the Ceyhan River, is the
second stop on the historical Silk Road after Adana.
The history of Misis possibly starts with its tumulus
(6000 B.C.).
It is said that Mopsus, one of the heroes of Troy, established
Misis.
It was controlled by
Hittites, Assyrians, Macedonians, and later became an
important center in the Roman and Byzantine periods.
In was restored in the 8th century during the Abbasi
period. After 1517, Misis became part of the Ottoman
Empire.
The city contains mosaics from
the 4th century A.D., a stone bridge with nine arches, city
wall ruins in Akropal, the Havraniye Caravanserai, built in
1542, and a little mosque with one dome.